A friend of mine had a heart transplant not too long ago and they were wondering if it was safe to smoke weed. I've heard that weed can mess with the immunosuppressants, is this true? What other negative effects could come out of smoking? My friend has never smoked weed, and really wants to... But I'm glad we didn't because he could have died with the elevated heart rate over a long period of time. But since this is with a new heart and the old heart was the problem, nothing else wrong with them, they are really healthy. I would really like to toke with my friend but I want to make sure he's safe. So what are your thoughts? ~Thanks!